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Bannière Centre d’excellence en neuromiquebande grise





Pierre Duquette, M.D.

Pierre Duquette is full professor at the Faculty of Medicine of the Université de Montréal.




Centre hospitalier de l’Université de Montréal
1560 Sherbrooke Street E
Montreal, Quebec
Canada H2L 4M1

Phone: 514-890-8000 extension 26848
Fax: 514-412-7668
Email :pierre.duquette.1@umontreal.ca


Dr. Pierre Duquette’s research work is based on the use of magnetic resonance to explore the pathological abnormalities of multiple sclerosis (MS). Dr. Duquette is also interested in the genetic abnormalities associated with MS and the role B-lymphocytes have in the disease.


Multiple sclerosis


Sajja BR, Narayana PA, Wolinsky JS, Ahn CW; PROMiSe Trial MRSI Group. Longitudinal magnetic resonance spectroscopic imaging of primary progressive multiple sclerosis patients treated with glatiramer acetate: multicenter study. Mult Scler. 2008 Jan;14(1):73-80. Epub 2007 Sep 19.

Sadovnick AD, Duquette P, Herrera B, Yee IM, Ebers GC. A timing-of-birth effect on multiple sclerosis clinical phenotype. Neurology. 2007 Jul 3;69(1):60-2.

Boucher A, Desforges M, Duquette P, Talbot PJ. Long-term human coronavirus-myelin cross-reactive T-cell clones derived from multiple sclerosis patients. Clin Immunol. 2007 Jun;123(3):258-67. Epub 2007 Apr 19.

Ifergan I, Wosik K, Cayrol R, Kébir H, Auger C, Bernard M, Bouthillier A, Moumdjian R, Duquette P, Prat A. Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis. Ann Neurol. 2006 Jul;60(1):45-55

Kinkel RP, Kollman C, O'Connor P, Murray TJ, Simon J, Arnold D, Bakshi R, Weinstock-Gutman B, Brod S, Cooper J, Duquette P, Eggenberger E, Felton W, Fox R, Freedman M, Galetta S, Goodman A, Guarnaccia J, Hashimoto S, Horowitz S, Javerbaum J, Kasper L, Kaufman M, Kerson L, Mass M, Rammohan K, Reiss M, Rolak L, Rose J, Scott T, Selhorst J, Shin R, Smith C, Stuart W, Thurston S, Wall M; CHAMPIONS Study Group. IM interferon beta-1a delays definite multiple sclerosis 5 years after a first demyelinating event. Neurology. 2006 Mar 14;66(5):678-84. Epub 2006 Jan 25.

Auger C, Montplaisir J, Duquette P. Increased frequency of restless legs syndrome in a French-Canadian population with multiple sclerosis. Neurology. 2005 Nov 22;65(10):1652-3.

Duquette P. Interferons in MS Treatment: report from the Canadian MS Forum symposium, 26-29 August 2004, Québec, Canada. Int MS J. 2005 Apr;12(1):33-4.

Freedman MS, Francis GS, Sanders EA, Rice GP, O'Connor P, Comi G, Duquette P, Metz L, Murray TJ, Bouchard JP, Abramsky O, Pelletier J, O'Brien F; Once Weekly Interferon beta-1alpha for Multiple Sclerosis Study Group; University of British Columbia MS/MRI Research Group. Randomized study of once-weekly interferon beta-1la therapy in relapsing multiple sclerosis: three-year data from the OWIMS study. Mult Scler. 2005 Feb;11(1):41-5.

Metz LM, Zhang Y, Yeung M, Patry DG, Bell RB, Stoian CA, Yong VW, Patten SB, Duquette P, Antel JP, Mitchell JR. Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis. Ann Neurol. 2004 May;55(5):756.

Qin Y, Duquette P. B-cell immunity in MS. Int MS J. 2003 Dec;10(4):110-20. Review.

Dwosh E, Guimond C, Duquette P, Sadovnick AD. The interaction of MS and pregnancy: a critical review. Int MS J. 2003 Jun;10(2):38-42. Review.


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